Adaptive Mistranslation Accelerates the Evolution of Fluconazole Resistance and Induces Major Genomic and Gene Expression Alterations in Candida albicans
Regulated erroneous protein translation (adaptive mistranslation) increases proteome diversity and produces advantageous phenotypic variability in the human pathogen Candida albicans. It also increases fitness in the presence of fluconazole, but the underlying molecular mechanism is not understood....
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Format: | Article |
Published: |
2017
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Series: | mSPHERE
2 No. 4 |
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mtmt: | 30439623 |
Online Access: | https://publikacio.ppke.hu/1684 |